| Much of today’s high visibility, cutting-edge microarray technology entails the use of high-throughput systems such as sophisticated robotics that require large capital expenditures. There is a large population of researchers who do not have access to robotic arrayers and who want to screen or study a small collection of molecules. As an alternative to robotic arrayers, the MicroCaster™ can be used as a tool for hand-arraying molecules onto FAST™ Slides in a microarray format. The use of nitrocellulose as a matrix to immobilize nucleic acids targeting the hybridization of their complementary sequences has been well documented in the literature. |
It has served as a key tool for molecular biologists who have employed it in Southern, Northern, and Western blotting procedures. These procedures, which have been modified and miniaturized to create microarrays, continue to form the backbone of scientific discovery. Microarray technology allows researchers to screen large libraries of molecules such as DNA and proteins in time-spans that previously would not have been feasible. This technology provides the tools necessary to begin the process of deciphering the functional aspects of sequences buried within the human genome. To continue reading, please click here to download the full PDF file (122kb) |
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